Ukukhula kweseli kunezidingo eziqinile ngendawo ezungezile, izinga lokushisa, inani le-PH, njll., futhi ikhwalithi yezinto ezisetshenziswa amaseli ezisetshenziswa kusiko lamaseli izophinde ibe nomthelela ekukhuleni kweseli.Imboni yamaseliiwukusebenziseka okuvamise ukusetshenziselwa isiko lamaseli anamathelayo, futhi ikhwalithi yawo ithintwa ikakhulukazi izici ezine.

I-1, ukukhiqizwa kwezinto ezingavuthiwe: impahla eluhlaza yekhwalithi ephezulu iyisisekelo semikhiqizo yekhwalithi ephezulu, i-cell factory impahla eluhlaza ye-polystyrene (PS), futhi kufanele ihambisane nezidingo zezinga le-USP Class VI, igama lihlola izinto zepulasitiki. emkhakheni wezokwelapha kanye nemikhiqizo yamapayipi ekusetshenzisweni kwe-biomedical yokuhlolwa okuqinile, kuhambisana nokucaciswa kwezifundo zaselabhorethri ezingezona ezomtholampilo.

2, indawo yokukhiqiza: amaseli azwela kakhulu endaweni yokukhula, ngakho-ke kuyadingeka ukuthi okusebenzisekayo akumele kuqukathe i-endotoxin nezinye izinto eziyingozi kumaseli, okubeka phambili izidingo eziphakeme zendawo yokukhiqiza.Izinto ezisetshenziswayo zizokhiqizwa ekamelweni elihlanzekile eliyizinkulungwane eziyishumi, futhi kuzoqinisekiswa ngokuqinile (ukutholwa kwe-plankton, amagciwane e-sedimentation kanye nezinhlayiya ezimisiwe).Ukuphathwa kwekhwalithi kuzokwenziwa ngokuhambisana neshabhu ye-GMP ukuze kuqinisekiswe ukuzinza kwendawo yokukhiqiza.

3, ukulawulwa kwenqubo yokukhiqiza: lokhu kubhekisela kumkhiqizo ekukhiqizeni isixhumanisi ngasinye kufaka phakathi, njengemingcele yomjovo, izinga lokushisa lomjovo, njll., okuzothinta ikhwalithi yomkhiqizo ophelile.

I-4, ukuhlolwa kwekhwalithi: ukuhlolwa kwekhwalithi kuyinqubo ebalulekile ngemva kokuphothulwa kokukhiqizwa kwefekthri yeseli, izinto okufanele zihlolwe zihlanganisa ukubekwa uphawu, ukuphepha kwebhayoloji, ukuphepha ngokomzimba namakhemikhali, ukuqinisekiswa kokuqinisekiswa komkhiqizo, i-surface hydrophilicity, njll., ngokusebenzisa lezi zivivinyo ukuze kunqunywe. ukuthi imikhiqizo iyahlangabezana yini namazinga ekhwalithi.

Izici ezithinta ikhwalithi yezimboni zamaseli ikakhulukazi zihlanganisa izici ezine ezingenhla.Kuphela ngokulawula lezi zici kahle singakwazi ukukhiqiza imikhiqizo yekhwalithi ephezulu futhi ngaleyo ndlela sinikeze indawo enhle yokukhula kwamaseli.